As one kind of the xanthene, rhodamine fluorophores have attracted much attention because of its good water solubility, high fluorescence quantum yield, molar extinction coefficient and mitochondrial targeting compared with other fluorophores. Moreover, due to the unique "on-off" property of the screw ring, this type of dye has become one of the most extensive dye platforms for the construction of various fluorescent probes.
Fig. 1 Chemical structure of rhodamine fluorophore
Rhodamine fluorophores and their derivatives have been used in metal ion detection, analytical chemistry, PH spectral probe and other fields. Examples are as followed:
Fig. 2 Two structures for Hg2+detection probes
Fig. 3 Possible recognition mechanism of RGP 
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