- Home
- Products
- Fluorescent Probes
- Membrane Potential Probes
Membrane potential is the voltage difference between the inside and outside of a cell that powers the various molecules embedded in the membrane, which contain mitochondria membrane, myocardial membrane, neurons and so on. Especially, Mitochondria as the main energy supply structure of organisms, its electrical potential is an important physiological parameter employed to monitor health states of cells. Recently, classical fluorescent dyes, which contain TMRM (tetramethyl rhodamine methyl ester), TMRE (tetramethyl rhodamine ethyl ester), Rhodamine 123 (Rh 123), and JC-1 cationic groups, have been developed to synthesize membrane potential probes.
Fig.1 Structure of neurons, heart and mitochondria
Due to the special status of mitochondria, mitochondrial membrane potential detection technology has attracted extensive attention and research. The following is a brief introduction of the latest research progress of mitochondrial membrane potential probes, in order to provide reference for researchers.
Fig.2 Structures of TPP-based probe 1 and 2.
Fig.3 a) Chemical reaction of MAL components. b) Theoretical illustration of the cellular distribution of MAL reagents in different cellular compartments
Alfa chemistry provides various membrane potential probes and related services for researchers, if you can not find the product what you want in the catalog, please contact us, we will provide professional services.
Please kindly note that our products and services are for research use only.
Privacy Policy | Cookie Policy | Copyright © 2025 Alfa Chemistry. All rights reserved.