AIE Fluorescent Microspheres

Introduction

Aggregation-induced emission (AIE) fluorescent microspheres are fluorescent microspheres with AIE characteristics. Unlike conventional fluorescent materials, which often suffer from aggregation-induced quenching (ACQ), AIE fluorescent microspheres become more emissive upon aggregation. These microspheres are usually composed of polymers and small molecules with AIE properties. They can be synthesized in a variety of sizes, from nanometers to microns, and can be functionalized for specific applications. For example, AIE fluorescent microspheres can be used in biotechnology, nanomedicine, materials science, and environmental monitoring.

As a professional company of AIE fluorescent microspheres, Alfa Chemistry is dedicated in providing AIE fluorescent microspheres in various types to cater to diverse research needs. Here are the common AIE fluorescent microspheres we can offer.

Technical Parameters

CompositionPolystyrene (PS)

Particle Size Range50nm – 500nm

Particle Size UniformityCV ＜5%

Solid Content1wt%

Surface ModificationCarboxyl, amino, epoxide groups, etc.

AdditiveTrace amounts of surfactant

Storage2 – 8℃ (Do not freeze)

Shelf Life2 years

Product Name	Catalog	Optimum emission wavelength	Maximum emission wavelength	Particle size	Solid content	Package size
Carboxylate-Modified Microspheres (Blue)	PHC-LM-0001	365nm	415nm	200nm	1%	5ml,10ml,25ml
Carboxylate-Modified Microspheres (Green)	PHC-LM-0002	400nm	530nm	50nm	1%	5ml,10ml,25ml
	PHC-LM-0003	400nm	530nm	100nm	1%	5ml,10ml,25ml
	PHC-LM-0004	400nm	530nm	200nm	1%	5ml,10ml,25ml
	PHC-LM-0005	400nm	530nm	300nm	1%	5ml,10ml,25ml
	PHC-LM-0006	400nm	530nm	400nm	1%	5ml,10ml,25ml
Carboxylate-Modified Microspheres (Red)	PHC-LM-0007	365nm	610nm	200nm	1%	5ml,10ml,25ml
	PHC-LM-0008	365nm	610nm	300nm	1%	5ml,10ml,25ml
	PHC-LM-0009	365nm	610nm	400nm	1%	5ml,10ml,25ml
Carboxylate-Modified Microspheres (Yellow)	PHC-LM-0010	400nm	550nm	200nm	1%	5ml,10ml,25ml
	PHC-LM-0011	400nm	550nm	300nm	1%	5ml,10ml,25ml
	PHC-LM-0012	400nm	550nm	400nm	1%	5ml,10ml,25ml
Amine-Modified Microspheres (Green)	PHC-LM-0013	400nm	530nm	200nm	1%	5ml,10ml,25ml
Epoxy-Modified Microspheres (Green)	PHC-LM-0014	400nm	530nm	200nm	1%	5ml,10ml,25ml

Applications

Biomedical Imaging

FLISA

ELISA

LFCA

AIE fluorescent microspheres hold great promise in biomedical imaging due to their unique properties and versatility. They can be widely used as a valuable tool for biomedical imaging applications, paving the way for advances in basic research, diagnosis, and clinical translation, such as in cell labeling and tracking, intracellular imaging, tissue imaging, in vivo imaging, fluorescence-guided surgery, etc.

FLISA (fluorescence-linked immunosorbent assay) is a variation of the traditional ELISA (enzyme-linked immunosorbent assay) technology that uses fluorescence rather than enzyme activity to detect and quantify the presence of specific analytes. By leveraging the advantages of AIE fluorescent microspheres, researchers can develop sensitive, reliable, and high-throughput FLISA assays for a wide range of biomedical and clinical applications, such as biomarker detection, disease diagnosis, and drug discovery.

Integrating AIE fluorescent microspheres into ELISA (enzyme-linked immunosorbent assay) assays has many benefits, including enhanced sensitivity, multiplexing capabilities, reduced background noise, and compatibility with automated platforms. These advantages make AIE fluorescent microspheres widely used in research, diagnosis and drug development.

Integrating AIE fluorescent microspheres into LFCA (lateral flow chromatographic assay) assays offers a number of advantages, including enhanced sensitivity, multiplexing capabilities, quantitative analysis, improved stability, etc. These benefits make AIE microspheres an invaluable tool for the development of rapid and reliable diagnostic tests for a variety of applications including clinical diagnostics, environmental monitoring, food safety, and point-of-care testing.

Product Features

As a leading supplier of AIE fluorescent microspheres, Alfa Chemistry is committed to providing researchers with advanced fluorescent labeling solutions to drive innovation and progress in a variety of fields. Here are the features of our products.

01

Anti-quenching

Good fluorescence stability.

02

Uniform particle size

Ensure the quality of back-end products.

03

Large Stokes shifts

Good fluorescence stability.

04

High amount of surface modifying groups

Sufficient quantities of target proteins can be coupled efficiently.

05

Customizable

We can customize products according to customer requirements.

As a provider of AIE fluorescent microspheres, Alfa Chemistry serves you wholeheartedly in the field of AIE solutions. Please check out our state-of-the-art AIE fluorescent microspheres - the ultimate solution for all your fluorescence imaging and detection needs. Please feel free to contact us to learn more.